16-week-old Dogue de Bordeaux x English Mastiff puppy laying down in the grass
The Muscle Mastiff is not a purebred dog. It is a cross between the Dogue de Bordeaux and the Mastiff. The best way to determine the temperament of a mixed breed is to look up all breeds in the cross and know you can get any combination of any of the characteristics found in either breed. Not all of these designer hybrid dogs being bred are 50% purebred to 50% purebred. It is very common for breeders to breed multi-generation crosses.